Do, Maragret (2012) Important concepts and elements of gene expression & RNA biology. Research World, Delhi, India. ISBN 9788132333111
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Abstract
Regulation of gene expression (or gene regulation) includes the processes that cells and viruses use to regulate the way that the information in genes is turned into gene products. Although a functional gene product may be an RNA or a protein, the majority of known mechanisms regulate protein coding genes. Any step of the gene's expression may be modulated, from DNA-RNA transcription to the post-translational modification of a protein. Gene regulation is essential for viruses, prokaryotes and eukaryotes as it increases the versatility and adaptability of an organism by allowing the cell to express protein when needed. The first discovered example of a gene regulation system was the lac operon, discovered by Jacques Monod, in which proteins involved in lactose metabolism are expressed by E. coli only in the presence of lactose and absence of glucose. Furthermore, gene regulation drives the processes of cellular differentiation and morphogenesis, leading to the creation of different cell types in multicellular organisms where the different types of cells may possess different gene expression profiles even though they all possess the same genome sequence.
| Item Type: | Book |
|---|---|
| Subjects: | Q Science > QH Natural history > QH301 Biology |
| Divisions: | Electronic Books |
| Depositing User: | Esam @ Hisham Muhammad |
| Date Deposited: | 02 Jan 2023 02:12 |
| Last Modified: | 02 Jan 2023 02:12 |
| URI: | http://odlsystem2.utm.my/id/eprint/3901 |
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